I have been using your 4-5-1 against the grain tactic on three different saves.
One with a top club (Juventus), don't think I even lost one game. (played two seasons)
Then with a crappy Norwegian second division team, which performed above all expectations. (Was predicted 12th, finished 5th, mind you I took over in the middle of the season so there was certain limitations as to how I could finish)
And lastly with a German second division team (though here I have been having some problems), but I don't think it is the tactics fault.
As in many matches I had the most CCC's and statistically