I've been enjoying a save with River Plate and documenting it in River Plate Take Two - The Hook.
Presumably most of you won't want to read it so I'll summarise: 2 Copa Libertadores, 2 Recopa and 1 Superliga (clinched in a derby game on the final day of the season, which was special). The tactic:
I almost never actually use CD-De - CD-De. I customise to the players so its some combination of CD and BPD either Cover-Defend, Cover-Stopper or Defend-Stopper.