I play the same tactic home and away. I make small adjustments to my 4-1-4-1 possession tactic depending on how the opposition plays and how my team reacts. If we have plenty of possession but don't create chances against a 4-4-2, I'll add the shout Exploit the Middle. Against a 3-5-2 I will Exploit the Flanks, as long as I have Keep Possession on as well. If we are up against a much bigger team that is pinning me back, I have recently went strikerless with a 4-1-4-1-0. The strikerless tactic creates fewer chances, but is better for possession.
In big matches I try to watch the first 5 minutes just to get a feel for the game. After that I switch to Comprehensive.