it depends on which team youre playing as and also what you call a big gap as some leagues have mid season break like over winter so might be a good idea to just play your reserves to help those who are slightly injured or are injured to recover before you next game
In Romania there is a mid-season break from December 16 till February 20 or so.
Almost 2 months, it would be foolish not to play some friendlies. So it depends on the gap. In Italy for example where there are two weeks of "holiday" I wouldn't play any game.
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