A little help please?

right iv installed the game and it runs perfectly for how ever long i wana play it for but when i wana quit i save the game then quit

but the problem is when i wana start the game back up a few hours later iv got to un-install the game then install it again as it doesnt start up any other way at all

any help please?

You need to tell us why it doesn't start - what happens?

And more about your PC would be useful - a DXDiag would be a good start.