Does preffered foot matter for defenders when defending?

Just a simple question really, if playing against wingers who are constantly running inside would it better to use full backs who are the other foot to the side which they play on. I.e left footed playing right back, rather than just right footed right back? Or even centre backs, if you're playing against Van Persie, it'd be better for a right footed centre back to mark him in order to be on his strong foot when making the tackle/block when Van Persie tries to use his favoured left foot.

I was just wondering in FM game world, if this matters at all or anyone found they have better results by doing something similar to what's been said?